PUBLICACIONES

• Perioperative Nivolumab and Chemotherapy in Stage III Non–Small-Cell Lung Cancer
  M. Provencio, E. Nadal, J.L. Gonzalez‑Larriba, A. Martinez‑Marti, R. Bernabe, J. Bosch‑Barrera, J. Casal‑Rubio, V. Calvo, A. Insa, S. Ponce, N. Reguart, J. de Castro, J. Mosquera, M. Cobo, A. Aguilar, G. Lopez Vivanco, C. Camps, R. Lopez‑Castro, T. Moran, I. Barneto, D. Rodriguez‑Abreu, R. Serna‑Blasco, R. Benitez, C. Aguado de la Rosa, R. Palmero, F. Hernando‑Trancho, J. Martin‑Lopez, A. Cruz‑Bermudez, B. Massuti, and A. Romero
  NADIM II
  N Engl J Med. 2023 Aug 10; 389(6): 504-513
  DOI: 10.1056/NEJMoa2215530

 

• Phase II Trial of Atezolizumab Combined with Carboplatin and Pemetrexed for Patients with Advanced Non-Squamous NSCLC with Untreated Brain Metastases (Atezo-Brain, GECP17/05)
  Ernest Nadal,1,2 Delvys Rodríguez-Abreu,3 Marta Simó,4 Bartomeu Massutí,5 Oscar Juan,6 Gerardo Huidobro,7 Rafael López,8 Javier De Castro,9 Anna Estival,10 Rosario Garcia-Campelo,11 Ivana Sullivan,12 Enriqueta Felip,13 Ana Blasco,14 Maria Guirado,15 Eva Pereira,16 Noelia Vilariño,1,2 Valentín Navarro,1 Jordi Bruna4
  ATEZO-BRAIN _JCO
  https://ascopubs.org/doi/10.1200/JCO.22.02561

 

• Immunogenicity of COVID‑19 vaccines in lung cancer patients: a SOLID substudy analysis
  Mariano Provencio, Anna Estival, Fernando Franco, Guillermo López Vivanco, Maria Saigí, Hugo Arasanz, Pilar Diz, Enric Carcereny, Javier Garcia, Carlos Aguado, Joaquin Mosquera, Virginia Calvo, xxxx, Margarita Majem, Joaquim Bosch-Barrerra, Xavier Mielgo, María Guirado, Oscar Juan-Vidal, Ana Blasco, Clara L. Gozálvez, Anabel del Barrio, Teresa de Portugal, Ana López-Martín, Gloria Serrano, Begoña Campos, Judit Rubio, Silvia Catot, Beatriz Esteban, Juan Luís Martí Ciriquian, Edel del barco,
  Solid III
  Lung Cancer 184 (2023)107323 | https://doi.org/10.1016/j.lungcan.2023.107323

 

• Pembrolizumab as first-line treatment for advanced NSCLC in older adults: A phase II clinical trial evaluating geriatric and quality-of-life outcomes
  Remei Blanco, MD, PhD,a,* Manuel Dómine, MD, PhD,b José Luis González Larriba, MD, PhD,c Sami Loutfi, MD,d Jordi Alfaro, MD,a Juana Saldaña, MD,e Jaime Rubio-Perez, MD, PhD,b Begoña Campos, MD,f Julia Hidalgo-Coloma, MD,g Andrés Barba, MD,h Diego Márquez-Medina, MD, PhD,i Maria Martin, MD, PhD,j Amaya Olaverri, MD,k Ernest Nadal, MD, PhDe on behalf of the Spanish Lung Cancer Group
  PEBEL
  Lung Cancer 183 (2023) 107318 | https://doi.org/10.1016/j.lungcan.2023.107318

 

• Difficulties on the access to innovative targeted therapies for lung cancer in Spain
  Virginia Calvo1, Carlos Camps2, Enric Carcereny3, Manuel Cobo4, Manuel Dómine5, María Rosario García Campelo6, José Luis González Larriba7, María Guirado8, Florentino Hernando Trancho9, Bartomeu Massutí10; Ernest Nadal11, Delvys Rodríguez-Abreu12, Alfredo Sánchez13, Ivana Gabriela Sullivan14, Mariano Provencio1 on behalf of the Spanish Lung Cancer Group (SLCG / GECP).
  Proyecto Retrasos Innovación.
  Clinical and Translational Oncology | https://doi.org/10.1007/s12094-023-03303-5

 

• Machine Learning-Assisted Recurrence Prediction for Early-Stage Non-Small-Cell Lung Cancer Patients
  Adrianna Janik1, Maria Torrente2, Luca Costabello1, Virginia Calvo2, Brian Walsh3,4, Carlos Camps5 Sameh K. Mohamed3,4, Ana L. Ortega6. Vít Nováček3,4,9,10, Bartomeu Massutí7, Pasquale Minervini8, M.Rosario Garcia Campelo11, Edel del Barco12, Joaquim Bosch-Barrera13, Ernestina Menasalvas14, Mohan Timilsina3,4, Mariano Provencio2
  CLARIFY
  JCO Clinical Cancer Informatics 2023: 7 | https://doi.org/10.1200/CCI.22.00062

 

• Synergy between imputed genetic pathway and clinical information for predicting recurrence in early stage non-small cell lung cancer
  Mohan Timilsinaa,∗, Dirk Feyb, Samuele Buosia, Adrianna Janike, Luca Costabelloe, Enric Carcereny, Delvys Rodrıguez Abreu, Manuel Cobo, Rafael Lo´pez Castro, Reyes Bernabé, Pasquale Minervinif, Maria Torrenteg, Mariano Provenciog and Vít Nováčeka,c,d
  CLARIFY
  Journal of Biomedical Informatics 144 (2023) 104424 | https://doi.org/10.1016/j.jbi.2023.104424

 

• Real-world treatment patterns and survival outcomes for patients with stage III NSCLC in Spain: a nationwide registry analysis
  Mariano Provencio1, Eric Carcereny2, Rafael López Castro3, Virginia Calvo4, Delvys Rodríguez Abreu5, Manuel Cobo6, Ana Laura Ortega7, Reyes Bernabé8, Maria Guirado9, Bartomeu Massutí10, Edel del Barco11, Joaquim Bosch-Barrera12, Carlos Camps13, Robert Carroll14, Caroline Raultx, Laure Lacoin15, Carlos Chaib16, John Penrod17, Lein Vox, Eleanor Ralphs,18 Melinda Daumont19
  RTT – Optimise
  Transl Lung Cancer Res 2023;12(10):2113-2128 | https://dx.doi.org/10.21037/tlcr-23-176

 

• Addressing lung cancer screening eligibility in Spain using 2013 and 2021 US Preventive Service Task Force criteria: cross-sectional study
  Cristina Candal-Pedreira1,2, Alberto Ruano-Ravina 1,2,3, Virginia Calvo de Juan4, Manuel Cobo5, José Manuel Trigo5, Enric Carcereny6, Marc Cucurull6, Rafael López Castro7, Eduardo Solís García7, Amparo Sánchez-Gastaldo8, Bartomeu Massutí9, Delvys Rodríguez-Abreu10, Anna Estival10, María Guirado Risueño11, María Pamiés Ramón11, Rosario García Campelo12, Guillermo Alonso-Jáudenes12, Carlos Camps13,14,15, Edel del Barco Morillo16, Clara González Ojea17, Manuel Dómine18, Alfredo Sanchez-Hernandez19, Joaquím Bosch-Barrera20, María Ángeles Sala González21 and Mariano Provencio4
  RTT – cumplimiento de los criterios de screening de cáncer de pulmón
  ERJ Open Res 2023; 9: 00468-2023 | https://doi.org/10.1183/23120541.00468-2023

• Seroprevalence and immunological memory against SARS-CoV-2 in lung cancer patients: the SOLID study
  Mariano Provencio, MD, PhD, Delvys Rodríguez-Abreu MD, Ana Laura Ortega MD, Gloria Serrano MD, Carlos Aguado MD, Fernando Franco MD, Vanesa Gutierrez MD, Guillermo López Vivanco MD, María Guirado MD, Gretel Benítez MD , Anna Estival MD, Virginia Calvo MD, Beatriz Jiménez MD, Hugo Arasanz MD , Juan Coves MD , Margarita Majem MD, Bartomeu Massutí MD , Sergio Vázquez MD, Oscar Juan-Vidal MD, Ana Collazo MD, Clara Lucía Gozálvez MD, Edel Del Barco MD, Adriana Rosero MD, Joaquim Bosch-Barrerra MD, María Ángeles Moreno MD, Xavier Mielgo MD, Juan Carlos Villa MD, Ana López-Martin MD, Juan Felipe Córdoba MD, Francisco de Asís Aparici MD, Marta Zafra MD, Joaquin Mosquera MD, Javier Pérez Altozano MD, Ernest Nadal MD, Silvia Catot MD, José Balsalobre MD, Teresa de Portugal MD, Paloma Martín MD, Susana Cuesta de Juan MD, Manuel Cobo MD.
  Transl Lung Cancer Res 2021 | https://dx.doi.org/10.21037/tlcr-21-504

 

• Clinical impact of delays in the management of lung cancer patients in the last decade: systematic review
  María Guirado1 · Elena Fernández Martín2 · Alberto Fernández Villar3 · Arturo Navarro Martín4 · Alfredo Sanchez‑Hernandez5
  Clinical and Translational Oncology volume 24, pages1549–1568 (2022) | https://doi.org/10.1007/s12094-022-02796-w

 

• OVERALL SURVIVAL WITH NEOADJUVANT NIVOLUMAB PLUS CHEMOTHERAPY IN OPERABLE NSCLC. TISSUE AND PLASMA BIOMARKERS FOR THE PREDICTION OF LONG-TERM SURVIVAL RESULTS FROM NADIM TRIAL
  M.Provencio1*, R. Serna-Blasco1, E. Nadal2, A. Insa3, MR. García‑Campelo4, J. Casal5, M. Dómine6, M. Majem7, D. Rodríguez-Abreu8, A. Martinez-Marti9, J. De Castro Carpeño10, M. Cobo11, G. López Vivanco12, E. Del Barco13, R. Bernabé Caro14, N. Viñolas15, I. Barneto Aranda16, S. Viteri17, E Pereira18, A. Royuela1, V. Calvo1, J Martin1, García-García F19, M. Casarrubios1, R. Palmero2; E. Sánchez-Herrero1, B. Massuti20, A. Cruz-Bermúdez1, A. Romero1
  Journal of Clinical Oncology 2022 40:25, 2924-2933 | http://ascopubs.org/doi/full/10.1200/JCO.21.02660

 

• Representatividad del Registro de Tumores Torácicos de España. Comparación de datos sociodemográficos con otros registros nacionales
  Cristina Candal-Pedreira, Alberto Ruano-Ravina,∗, Enric Carcereny, Delvys Rodríguez-Abreu, María Guirado-Risueño, Rafael López-Castro, Bartomeu Massutí, Ana Blasco, Ana Laura Ortega, Mariano Provencio
  Gac Sanit. 2022; 36(6): 540-545 | https://doi.org/10.1016/j.gaceta.2022.02.013

 

• Determination of essential biomarkers in lung cancer: a real‑world data study in Spain with demographic, clinical, epidemiological and pathological characteristics
  Mariano Provencio1*, Manuel Cobo2, Delvys Rodriguez‑Abreu3, Virginia Calvo1, Enric Carcereny4, Alexandra Cantero2, Reyes Bernabe5, Gretel Benitez3, Rafael Lopez Castro6, Bartomeu Massuti7, Edel del Barco8, Rosario Garcia Campelo9, Maria Guirado10, Carlos Camps11,12,13, Ana Laura Ortega14, Jose Luis Gonzalez Larriba15, Alfredo Sanchez16, Joaquin Casal17, M. Angeles Sala18, Oscar Juan‑Vidal19, Joaquim Bosch‑Barrera20, Juana Oramas21, Manuel Domine22, Jose Manuel Trigo23, Remei Blanco24, Julia Calzas25, Idoia Morilla26, Airam Padilla27, Joao Pimentao28, Pedro A. Sousa28 and Maria Torrente1
  Provencio et al. BMC Cancer (2022) 22:732 | https://doi.org/10.1186/s12885-022-09830-8

 

• A prognostic score for patients with malignant pleural mesothelioma (MPM) receiving second-line immunotherapy or chemotherapy in the ETOP 9-15 PROMISE-meso phase III trial
  Giuseppe L Banna, Addeo A, Zygoura P, Tsourti Z, Popat S, Curioni-Fontecedro A, Nadal E, Shah R, Pope A, Fisher P, Spicer J, Roy A, Gilligan D, Gautschi O, Janthur WD, López-Castro R, Roschitzki-Voser H, Dafni U, Peters S, Stahel RA, on behalf of the ETOP 9-15 PROMISE-meso Collaborators
  Lung Cancer 169 (2022) 77-83 | https://doi.org/10.1016/j.lungcan.2022.05.018

 

• Tumor microenvironment gene expression profiles associated to complete pathological response and disease progression in resectable NSCLC patients treated with neoadjuvant chemoimmunotherapy.
  Marta Casarrubios1, Mariano Provencio1, Ernest Nadal2, Amelia Insa3, María del Rosario García‑Campelo4, Joaquín Casal-Rubio5, Manuel Dómine6, Margarita Majem7, Delvys Rodríguez-Abreu8, Alex Martínez-Martí9, Javier De Castro Carpeño10, Manuel Cobo11, Guillermo López Vivanco12, Edel Del Barco13, Reyes Bernabé Caro14, Nuria Viñolas15, Isidoro Barneto Aranda16, Bartomeu Massuti17, Belén Sierra-Rodero1, Cristina Martinez-Toledo1, Ismael Fernández-Miranda1, Roberto Serna-Blanco1, Atocha Romero1, Virginia Calvo1, Alberto Cruz-Bermúdez1*.
  J Immunother Cancer 2022;10:e005320. | https:// doi:10.1136/jitc-2022-005320

 

• Alectinib for the treatment of pretreated RET-rearranged advanced NSCLC: results of the ETOP
  ALERT-lung trial
  Enriqueta Felip1* Egbert Smit2* Miguel Angel Molina3, Urania Dafni4,5, Tomeo Massuti6, Tierry Berghmans7, Filipo de Marinis8, Silvia Novello9, Anne-Marie Dingemans10, Manuel Cobo Dols11, Santiago Viteri12, Christian Britschgi13, Sinead Cuffe14, Mariano Provencio15, Sabine Merkelbach-Bruse16, Rosita Kammler17, Barbara Ruepp17, Heidi Roschitzki-Voser17, Solange Peters18, Jürgen Wolf19, Rolf Stahel17#, on behalf of the ETOP 12-17 ALERT-lung Collaborators
  Lung Cancer 2022;172:94-99 | https://doi.org/10.1016/j.lungcan.2022.08.008

 

• A phase II open-label study of atezolizumab in combination with bevacizumab as first-line treatment for locally advanced or metastatic high tumor mutational burden selected nonsquamous non-small cell lung cancer patients. The TELMA study
  Mariano Provencio1, Ana Laura Ortega2, Juan Coves‑Sarto3, Virginia Calvo1, Raquel Marsé-Fabregat4, Manuel Dómine5, María Guirado6, Enric Carcereny7, N. Fernández8, Elia Martínez9, Remei Blanco10, Luis León‑Mateos11, José Miguel Sánchez‑Torres12, Ivana Gabriela Sullivan13, Manuel Cobo14, Alfredo Sánchez‑Hernández15, Bartomeu Massutí16, Belen Sierra-Rodero1, Cristina Martinez-Toledo1, Roberto Serna-Blanco1, Atocha Romero1, Alberto Cruz-
  JAMA Oncol. | https://doi:10.1001/jamaoncol.2022.5959

• Phase II Clinical Trial with Metronomic Oral Vinorelbine and Tri-weekly Cisplatin as Induction Therapy, Subsequently Concomitant with Radiotherapy (RT) in Patients with Locally Advanced, Unresectable, Non-Small Cell Lung Cancer (NSCLC). Analysis of Survival and Value of ctDNA for Patient Selection. (NORA)
  Mariano Provencio; Marga Majem, María Guirado, Bartomeu Massuti, Ramon de las Peñas, Ana Laura Ortega, Manuel Dómine, Raquel Marsé, Maria Ángeles Sala, Alfredo Paredes, Teresa Morán, Sergio Vázquez, Juan Coves, José Luis González Larriba, Jose Miguel Sánchez, David Vicente, Núria Farré, Luis Fernández Fornos, Irma Zapata, Roberto Serna, Atocha Romero, Dolores Isla
  Lung Cancer 153 (2021) 25–34 https://doi.org/10.1016/j.lungcan.2021.01.005

 

• Outcomes of surgical resection after neoadjuvant chemoimmunotherapy in stage IIIA non-small-cell lung cancer: Findings from the NADIM study
  Alejandra Romero Román* , Jose Luis Campo-Cañaveral de la Cruz*1, Ivan Macía , Ignacio Escobar Campuzano , Santiago Figueroa Almánzar , María Delgado Roel , Carlos Gálvez Muñoz , Eva Mª García Fontán, Ignacio Muguruza Trueba, Laura Romero Vielva, Jose Ramon Cano Garcia, Elisabeth Martinez Tellez , Concepción Partida González, Marcelo Fernando Jiménez López , Unai Jiménez Maestre, Roberto Mongil Poce, David Sánchez Lorente, Antonio Álvarez Kindelan, Mariano Provencio Pulla
  European Journal of Cardio-Thoracic Surgery 00 (2021)1-8 // doi: 10.1093/ejcts/ezab007

 

• Osimertinib monotherapy in advanced EGFR-T790M mutation-positive non-small-cell lung cancer (NSCLC) patients treated within the Special Use Medication Program (SUMP) in Spain. OSIREX-Spanish Lung Cancer Group
  Mariano Provencio, Josefa Terrasa; Pilar Garrido, Rosario Garcia Campelo, Francisco Aparisi, Pilar Diz, David Aguiar, Carlos García-Giron, Julia Hidalgo, Carlos Aguado, Jorge García González, Emilio Esteban, Lorenzo Gómez-Aldavarí, Teresa Moran, Oscar Juan, Luís Enrique Chara, Juan L. Marti, Rafael López Castro, Ana Laura Ortega, Elia Martínez Moreno, Juan Coves, Ana M. Sánchez Peña; Joaquim Bosch-Barrera; Amparo Sánchez Gastaldo; Natalia Fernández Núñez; Edel del Barco; Manuel Cobo; Dolores Isla; Margarita Majem; Fátima Navarro; Virginia Calvo
  BMC Cancer (2021)21:230 // https:doi.org/10.1186/s12885-021-07922-5

 

• Analysis of circulating tumor DNA to identify EGFR positive NSCLC patients at low risk of progression who can benefit from sequential Tyrosine Kinase Inhibitor treatment
  Mariano Provencio1, Roberto Serna Blasco1, Fabio Franco1, Virgina Calvo1, Ana Royuela1, Mylda Agluite1, Alfredo Sánchez2, Maria de Julian Campayo2, Carlos García Girón3, Manuel Dómine4, Eloisa Jantus5, José Miguel Sánchez6, Juana Oramas7, Joaquim Bosch-Barrera8, María Ángeles Salas9, María Sereno10, Ana Laura Ortega11, Luis Chara12, Berta Hernández13, Airam Padilla14, Juan Coves15, Remei Blanco16, José Balsalobre17, Xavier Mielgo18, Coralia Bueno19, Atocha Romero1
  European Journal of Cancer 149 (2021) 61e72

 

• Spanish Lung Cancer Group SCAT trial: surgical audit to lymph node assessment based on IASLC recommendations
  José Ramón Jarabo Sarceda, Sergio Bolufer Nadal, Roberto Mongil Poce, Pedro López de Castro, Ramón Moreno Balsalobre, Juan Carlos Peñalver Cuesta, Raul Embún Flor7, Joaquín Pac Ferrer, Francisco Javier Algar Algar, Antonio Pablo Gámez García, Marcelo F. Jiménez, Jesús Gabriel Sales-Badía, Eva Pereira, Bartomeu Massuti, Mariano Provencio, Florentino Hernando Trancho,
  Transl Lung Cancer Res 2021 | http://dx.doi.org/10.21037/tlcr-20-1055

 

• Lung Cancer Patients with COVID-19 in Spain: GRAVID study
  Mariano Provencio1*; José María Mazarico Gallego2; Antonio Calles3; Mónica Antoñanzas4; Cristina Pangua5; Xabier Mielgo Rubio6; Ernest Nadal7; Rafael López Castro8; Ana López-Martín9; Edel del Barco10; Manuel Dómine11; Fernando Franco1; Pilar Diz12; Carmen Sandoval13; Elia Sais Girona14; Ivana Sullivan15; Mª Ángeles Sala16; Gema García Ledo17; Marc Cucurull18; Joaquín Mosquera19; Mireia Martínez20; Luis Enrique Chara21; Edurne Arriola22; Beatriz Esteban Herrera23; José Ramón Jarabo4; Rosa Álvarez Álvarez3; Javier Baena2; María González Cao24
  Lung Cancer https://doi.org/10.1016/j.lungcan.2021.05.014

 

• Epidemiology, treatment and survival of Small Cell Lung Cancer in Spain: information from the Thoracic Tumor Registry
  Fernando Francoa, Enric Carcerenyb, Maria Guiradoc, Ana L. Ortegad, Rafael Lopez-Castroe, Delvys Rodriguez-Abreuf, Rosario Garcia-Campelog, Edel del Barcoh, Oscar Juani, Ana Blascoj, Jose L Gonzalez-Larribak, Manuel Dominel, Jose M. Trigom, Manuel Cobon, Sara Cerezoo, Julia Calzasp, Bartomeu Massutíq, Joaquim Bosch-Barrera, Mariano Provencio,*
  PLOS ONE | https://doi.org/10.1371/journal.pone.0251761 June 2, 2021

 

• Blood biomarkers associated to complete pathological response on NSCLC patients treated with neoadjuvant chemoimmunotherapy included in NADIM clinical trial
  Raquel Laza-Briviesca1,2 Alberto Cruz-Bermúdez1 Ernest Nadal3 Amelia Insa4 María del Rosario García-Campelo5 Gerardo Huidobro6 Manuel Dómine7 Margarita Majem8 Delvys Rodríguez-Abreu9 Alex Martínez-Martí10 Javier De Castro Carpeño11 Manuel Cobo12 Guillermo López Vivanco13 Edel Del Barco14 Reyes Bernabé Caro15 Nuria Viñolas16 Isidoro Barneto Aranda17 Santiago Viteri18 Bartomeu Massuti19 Marta Casarrubios1,2 Belén Sierra-Rodero1,2 Carlos Tarín20 Aránzazu García-Grande21 Cara Haymaker22 Ignacio I. Wistuba22 Atocha Romero1 Fernando Franco1
  Clin. Transl. Med. 2021;11:e491. https://doi.org/10.1002/ctm2.491

 

• Prospective exploratory analysis of angiogenic biomarkers in advanced NSCLC patients treated with bevacizumab plus chemotherapy. The ANGIOMET study.
  Eloisa Jantus Lewintre1, Bartomeu Massutí Sureda2, Jose Luis González Larriba3, Delvys Rodríguez-Abreu4, Oscar Juan5, Manuel Dómine6, Mariano Provencio Pulla7, Javier de Castro8, Rafael Rosell9, Carlos Camps2 in behalf of Grupo Español de Cáncer de Pulmón (GECP)
  Front. Oncol., 26 July 2021 vol 11 /Article 695038 https://doi.org/10.3389/fonc.2021.695038

 

• TCR repertoire predicts complete pathological response in NSCLC patients receiving neoadjuvant chemoimmunotherapy from NADIM trial
  Marta Casarrubios1&, Alberto Cruz-Bermúdez1&*, Ernest Nadal2, Amelia Insa3, María del Rosario García‑Campelo4, Joaquín Casal-Rubio5, Manuel Dómine6, Margarita Majem7, Delvys Rodríguez-Abreu8, Alex Martínez-Martí9, Javier De Castro Carpeño10, Manuel Cobo11, Guillermo López Vivanco12, Edel Del Barco13, Reyes Bernabé Caro14, Nuria Viñolas15, Isidoro Barneto Aranda16, Santiago Viteri17, Bartomeu Massuti18, Miguel Barquín1, Raquel Laza-Briviesca1, Belén Sierra-Rodero1, Edwin R Parra19, Beatriz Sanchez-Espiridion19, Ignacio Wistuba19, Atocha Romero1, Virginia Calvo1, Mariano Provencio1*.
  Clin Cancer Res; Published Online First August 10, 2021; doi:10.1158/1078-0432.CCR-21-1200
  http://clincancerres.aacrjournals.org/content/early/2021/08/09/1078-0432.CCR-21-1200.abstract

 

• Clinical and Molecular Parameters Associated to Pneumonitis Development in Non-small Cell Lung Cancer Patients Receiving Neoadjuvant Chemoimmunotherapy from NADIM trial
  Belén Sierra-Rodero ,1 Alberto Cruz-Bermúdez ,1 Ernest Nadal ,2 Yago Garitaonaindía,1 Amelia Insa,3 Joaquín Mosquera,4 Joaquín Casal-Rubio,5 Manuel Dómine,6 Margarita Majem ,7 Delvys Rodriguez-Abreu,8 Alex Martinez-Marti ,9 Javier De Castro Carpeño,10 Manuel Cobo,11 Guillermo López Vivanco,12 Edel Del Barco,13 Reyes Bernabé Caro,14 Nuria Viñolas,15 Isidoro Barneto Aranda,16 Santiago Viteri,17 Bartomeu Massuti,18 Raquel Laza-Briviesca,1 Marta Casarrubios,1 Aránzazu García-Grande,19 Atocha Romero,1 Fernando Franco,1 Mariano Provencio 1
  J Immunother Cancer 2021;9:e002804. doi:10.1136/jitc-2021-002804

 

• Combined, patient-level, analysis of two randomised trials evaluating the addition of denosumab to standard first-line chemotherapy in advanced NSCLC – The ETOP/EORTC SPLENDOUR and AMGEN-249 trials
  Peters S, Danson S, Ejedepang D, Dafni U, Hasan B, Radcliffe H-S, Bustin F, Crequit J, Coate L, Guillot M, Surmont V, Rauch D, Rudzki J, O’Mahony D, Barneto Aranda I, Scherz A, Tsourti Z, Roschitzki-Voser H, Pochesci A, Demonty G, Stahel RA, O’Brien M..
  Lung Cancer 2021;161:76-85. doi: https://doi.org/10.1016/j.lungcan.2021.09.002. Epub 2021 September 9.

 

• Consolidation nivolumab and ipilimumab versus observation in limited-disease small cell lung cancer after chemo-radiotherapy – Results from the randomised phase II ETOP/IFCT 4-12 STIMULI trial
  Solange Peters*1, Jean-Louis Pujol*2,28, Urania Dafni3, Manuel Dómine4,29, Sanjay Popat5, Martin Reck6, Jesús Andrade7,29, Annemarie Becker8, Denis Moro-Sibilot9,28, Alessandra Curioni-Fontecedro10, Olivier Molinier11,28, Kristiaan Nackaerts12, Amelia Insa Mollá13,29, Radj Gervais14,28, Guillermo López Vivanco15,29, Jeannick Madelaine16,28, Julien Mazieres17,28, Martin Faehling18, Frank Griesinger19, Margarita Majem20,29, Jose Luis González Larriba21,29, Mariano Provencio Pulla22,29, Katerina Vervita23, Heidi Roschitzki-Voser24, Barbara Ruepp24, Paul Mitchell25,30, Rolf A. Stahel24#, Cécile Le Pechoux26,28‡, Dirk De Ruysscher27‡, on behalf of the ETOP/IFCT 4-12 STIMULI Collaborators
  Ann Oncol 2021; Epub ahead of print. doi: 10.1016/j.annonc.2021.09.011. Epub 2021 September 26.

 

• Seroprevalence and immunological memory against SARS-CoV-2 in lung cancer patients: the SOLID study
  Mariano Provencio, MD, PhD, Delvys Rodríguez-Abreu MD, Ana Laura Ortega MD, Gloria Serrano MD, Carlos Aguado MD, Fernando Franco MD, Vanesa Gutierrez MD, Guillermo López Vivanco MD, María Guirado MD, Gretel Benítez MD , Anna Estival MD, Virginia Calvo MD, Beatriz Jiménez MD, Hugo Arasanz MD , Juan Coves MD , Margarita Majem MD, Bartomeu Massutí MD , Sergio Vázquez MD, Oscar Juan-Vidal MD, Ana Collazo MD, Clara Lucía Gozálvez MD, Edel Del Barco MD, Adriana Rosero MD, Joaquim Bosch-Barrerra MD, María Ángeles Moreno MD, Xavier Mielgo MD, Juan Carlos Villa MD, Ana López-Martin MD, Juan Felipe Córdoba MD, Francisco de Asís Aparici MD, Marta Zafra MD, Joaquin Mosquera MD, Javier Pérez Altozano MD, Ernest Nadal MD, Silvia Catot MD, José Balsalobre MD, Teresa de Portugal MD, Paloma Martín MD, Susana Cuesta de Juan MD, Manuel Cobo MD.
  Transl Lung Cancer Res 2021 | https://dx.doi.org/10.21037/tlcr-21-504

 

• Prognostic model of long-term advanced stage (IIIB-IV) EGFR mutated non-small cell lung cancer (NSCLC) survivors using real-life data
  Lourdes Gutierrez, Enric Carcereny, Rafael Lopez-Castro, Delvys Rodríguez-Abreu, Bartomeu Massuti, Jose Luis González Larriba, Rosario García Campelo, Joaquim Bosh-Barrera, Maria Guirado, Carlos Camps, Manuel Dómine, Reyes Bernabé, Joaquin Casal, Juana Oramas, Ana Laura Ortega, Mª Angeles Sala, Airam Padilla, David Aguiar, Oscar Juan-Vidal, Remei Blanco, Edel del Barco, Ana Royuela PhD, Mariano Provencio.
  BMC Cancer // DOI: 10.1186/s12885-021-08713-8 https://pubmed.ncbi.nlm.nih.gov/34465283/

 

• Are there differences by sex in Lung cancer characteristics at diagnosis? A nationwide Study
  Alberto Ruano-Ravina,1,2,3 Mariano Provencio,4 Virginia Calvo de Juan,4 Enric Carcereny,5 Anna Estival,5 Delvys Rodríguez-Abreu,6 Gretel Benítez,6 Rafael López-Castro,7 Marta Belver,8 María Guirado-Risueño,9 Carlos Guirao-Rubio,9 Ana Blasco,10 Bartomeu Massutí,11 Ana Laura Ortega,12 Manuel Cobo,13 Joaquín Mosquera-Martínez,14 Carlos Aguado de la Rosa,15 Joaquim Bosch-Barrera,16,17 Autor Virgen Rocío,18 Edel del Barco Morillo,19 Óscar Juan,20 Manuel Dómine,21 José Manuel Trigo,22 Diego Pereiro Corbacho,23 Juana Oramas.24
  Transl Lung Cancer Res 2021 – https://tlcr.amegroups.com/article/view/57214/html

 

• A randomised phase II study of osimertinib and bevacizumab versus osimertinib alone as second-line treatment in advanced NSCLC with confirmed EGFR and T790M mutations: the European Thoracic Oncology Platform (ETOP 10-16) BOOSTER trial
  Ross A Soo*1, Ji-Youn Han*2, Urania Dafni3, Byoung Chul Cho4, Chong Ming Yeo5, Ernest Nadal6,27, Enric Carcereny7,27, Javier de Castro8,27, Maria Angeles Sala9,27, Bernabe Reyes10,27, Linda Coate11,28, Mariano Provencio Pulla12,27, Rosario Garcia Campelo13,27, Sinead Cuffe14,28, Sayed Hashemi15, Martin Früh16,29, Bartomeu Massuti17,27, Jose Garcia18,27, Manuel Dómine19,27, Margarita Majem20,27, Jose Miguel Sanchez21,27, Christian Britschgi22,29, Miklos Pless23,29, Georgia Dimopoulou24, Heidi Roschitzki-Voser25, Barbara Ruepp25, Rafael Rosell7, Rolf Stahel#25, Solange Peters26, on behalf of the ETOP 10-26 BOOSTER Collaborators
  Ann Oncol DOI: 10.1016/j.annonc.2021.11.010 – https://pubmed.ncbi.nlm.nih.gov/34839016/

 

• Quality Indicators and Excellence Requirements for a Multidisciplinary Lung Cancer Tumor Board by the Spanish Lung Cancer Group
  María Guirado, Alfredo Sanchez-Hernandez, Lara Pijuan,, Cristina Teixido, Antonio Gómez-Caamaño, Ángel Cilleruelo-Ramos
  Clinical and Translational Oncology https://doi.org/10.1007/s12094-021-02712-8

 

• Informe del GECP “Demoras y restricciones en el acceso a tratamientos innovadores para el cáncer de pulmón en España”.
  M. Provencio et al- Grupo Español de cáncer de pulmón
  Rev Esp- Econ. Salud V 16 / N 2. 2021

• Assessment of the Feasibility and Safety of Durvalumab for Treatment of Solid Tumors in Patients With HIV-1 Infection. The Phase 2 DURVAST Study
  Maria Gonzalez-Cao, MD, PhD; Teresa Morán, MD; Judith Dalmau, PhD; Javier Garcia-Corbacho, MD; Jillian W. P. Bracht, MSc; Reyes Bernabe, MD; Oscar Juan, MD; Javier de Castro, MD; Remei Blanco, MD; Ana Drozdowskyj, PhD; Jordi Argilaguet, PhD; Andreas Meyerhans, PhD0; Julia Blanco, PhD; Julia G. Prado, PhD; Jorge Carrillo, PhD; Bonaventura Clotet, MD; Bartomeu Massuti, MD; Mariano Provencio, MD; Miguel A. Molina-Vila, PhD; Clara Mayo de las Casa, PhD; Monica Garzon, PhD; Peng Cao, PhD; Chung-Ying Huang, PhD; Javier Martinez-Picado, PhD; Rafael Rosell, MD
  JAMA Oncol. Published online April 9, 2020. doi:10.1001/jamaoncol.2020.0465

 

• Sex is a strong prognostic factor in stage IV non-small-cell lung cancer patients and should be considered in survival rate estimation
  Miguel Barquín, Virginia Calvo, Francisco García-García, Beatriz Nuñez, Estela Sánchez-Herrero, Roberto Serna-Blasco, Milda Auglytė, Enric Carcereny, Delvys Rodriguez-Abreu, Rafael López Castro, María Guirado, Carlos Camps, Joaquín Bosch-Barrera, Bartomeu Massuti, Ana Laura Ortega, Edel del Barco, José Luis Gonzalez-Larriba, David Aguiar, Rosario García-Campelo, Manuel Dómine, Sara Agraso, Mª Angeles Sala, Juana Oramas, Reyes Bernabé, Remei Blanco, Consuelo Parejo, Alberto Cruz, Ernestina Menasalvas, Ana Royuela, Atocha Romero, Mariano Provencio
  Cancer Epidemiology 67 (2020) 101737

 

• Malignant pleural mesothelioma: treatment patterns and outcomes from the Spanish Lung Cancer Group
  Remon J, Nadal E, Dómine M, Ruffinelli J, García Y, Pardo JC; López R, Cilleruelo A, García-Campelo R, Martín-Martorell P, Juan O, González-Larriba JL, Provencio M, Olmedo E, Ponce S14, Cumplido D, Martínez-Barenys C, Majem M, Massutti B, Rodriguez-Abreu D, Porta R20, Sala MA, Martinez-Kareaga M, Lianes P, Reguart N.
  Lung Cancer 147 (2020)83-90
  Published:July 02, 2020DOI: https://doi.org/10.1016/j.lungcan.2020.06.034

 

• COMBINATION OF GEFITINIB AND OLAPARIB VERSUS GEFITINIB ALONE IN EGFR MUTANT NON-SMALL-CELL LUNG CANCER (NSCLC): A MULTICENTER, RANDOMIZED PHASE II STUDY (GOAL) – GOAL
  Rosario Garcia-Campelo,Oscar Arrieta, Bartomeu Massuti, Delvys Rodriguez-Abreu, Ana Laura Ortega Granados, Margarita Majem, David Vicente, Pilar Lianes, Joaquim Bosch-Barrera, Amelia Insa, Manuel Dómine, Noemí Reguart, María Guirado, María Ángeles Sala, Sergio Vázquez-Estevez, Reyes Bernabé Caro, Ana Drozdowskyj, Ana Verdú, Niki Karachaliou , Miguel Angel Molina-Vila, Rafael Rosell, On behalf of The Spanish Lung Cancer Group (SLCG)
  Lung Cancer 150 (2020) 62–69
  Published:October 03, 2020 DOI: https://doi.org/10.1016/j.lungcan.2020.09.018

 

• Neoadjuvant chemotherapy and nivolumab in resectable non-small-cell lung cancer (NADIM): an open-label, multicentre, single-arm, phase 2 trial
  Mariano Provencio, Ernest Nadal, Amelia Insa, María Rosario García-Campelo, Joaquín Casal-Rubio, Manuel Dómine, Margarita Majem, Delvys Rodríguez-Abreu, Alex Martínez-Martí, Javier De Castro Carpeño, Manuel Cobo, Guillermo López Vivanco, Edel Del Barco, Reyes Bernabé Caro, Nuria Viñolas, Isidoro Barneto Aranda, Santiago Viteri, Eva Pereira, Ana Royuela, Marta Casarrubios, Clara Salas Antón, Edwin R Parra, Ignacio Wistuba, Virginia Calvo, Raquel Laza-Briviesca, Atocha Romero, Bartomeu Massuti, Alberto Cruz-Bermúdez
  www.thelancet.com/oncology Published online September 24, 2020 https://doi.org/10.1016/S1470-2045(20)30453-8

 

• LUNG CANCER SYMPTOMS AT DIAGNOSIS: RESULTS OF A NATIONWIDE REGISTRY STUDY
  Alberto Ruano-Ravina,1,2 Mariano Provencio,3 Virginia Calvo de Juan,3 Enric Carcereny,4 María Teresa Morán,4 Delvys Rodríguez-Abreu,5 Rafael López-Castro,6 Eugenio Cuadrado-Albite,6 María Guirado,7 Lucía Gómez-González,7 Bartomeu Massutí,8 Ana Laura Ortega,9 Ana Blasco,10 Manuel Cobo,11 Rosario García Campelo,12 Joaquim Bosch,13,14 José Manuel Trigo,15 Óscar Juan,16 Carlos Aguado de la Rosa,17 Manuel Dómine,18 María Ángeles Sala,19 Juana Oramas,20 Joaquín Casal,21 Sara Cerezo.22
  ESMO Open 2020;5:e001021. doi:10.1136/esmoopen-2020-001021

 

• Comprehensive cross-platform comparison of methods for non-invasive EGFR mutation testing: Results of the RING observational trial.
  Atocha Romero,1,2 Eloisa Jantus-Lewintre,3,4,5 Beatriz García-Peláez,6 Ana Royuela,7 Amelia Insa,8 Patricia Cruz,9 Ana Collazo,10 Javier Pérez Altozano,11 Oscar Juan Vidal,12 Pilar Diz,13 Manuel Cobo,14 Berta Hernández,15 Sergio Vázquez Estevez,16 Gretel Benítez,17 Maria Guirado,18 Margarita Majem,19 Reyes Bernabé,20 Ana Laura Ortega,21 Ana Blasco,3,, Joaquim Bosch-Barrera,22 Jose M. Jurado,23 Jorge García González,24 Santiago Viteri,25 Carlos Garcia Giron,26 Bartomeu Massutí,27 Ana Lopez Martín,28 Alejandro Rodriguez-Festa,1 Silvia Calabuig-Fariñas,3,4,29 Miguel Ángel Molina-Vila,6 Mariano Provencio.1,
  Molecular Oncology, Publ. 26 octob 2020 https://doi.org/10.1002/1878-0261.12832

 

• BRCA1 expression and outcome in EGFR-mutant NSCLC patients treated with gefitinib alone or in combination with Olaparib
  Niki Karachaliou, Oscar Arrieta, Ana Giménez-Capitán, Erika Aldeguer, Ana Drozdowskyj, Imane Chaib, Noemí Reguart, Rosario Garcia-Campelo, Jing-Hua Chen, Miguel Angel Molina-Vila, Rafael Rosell, On behalf of The Spanish Lung Cancer Group (SLCG)
  JTO Clinical and Research Reports (2020), doi: https://doi.org/10.1016/j.jtocrr.2020.100113.

 

• A Randomized Open-Label Phase III Trial Evaluating the Addition of Denosumab to Standard First-Line Treatment in Advanced NSCLC: The European Thoracic Oncology Platform (ETOP) and European Organisation for Research and Treatment of Cancer (EORTC) SPLENDOUR Trial.
  Peters S, Danson S, Hasan B, Dafni U, Reinmuth N, Majem M, Tournoy KG, Mark MT, Pless M, Cobo M, Rodriguez-Abreu D, Falchero L, Moran T, Ortega Granados AL, Monnet I, Mohorcic K, Sureda BM, Betticher D, Demedts I, Macias JA, Cuffe S, Luciani A, Sanchez JG, Curioni-Fontecedro A, Gautschi O, Price G, Coate L, von Moos R, Zielinski C, Provencio M, Menis J, Ruepp B, Pochesci A, Roschitzki-Voser H, Besse B, Rabaglio M, O’Brien MER, Stahel RA.
  J Thorac Oncol 2020;15(10):1647-1656. doi: 10.1016/j.jtho.2020.06.011. Epub 2020 June 23.

 

• A multicentre randomised phase III trial comparing pembrolizumab versus single-agent chemotherapy for advanced pre-treated malignant pleural mesothelioma: the European Thoracic Oncology Platform (ETOP 9-15) PROMISE-meso trial
  S. Popat1y, A. Curioni-Fontecedro2y, U. Dafni3, R. Shah4,M. O’Brien5,A.Pope6, P. Fisher7, J. Spicer8, A. Roy9, D. Gilligan10, O. Gautschi11,12, E. Nadal13, W. D. Janthur12,14, R. López Castro15, R. García Campelo16, S. Rusakiewicz17, I. Letovanec18, V. Polydoropoulou19, H. Roschitzki-Voser20, B. Ruepp20, A. Gasca-Ruchti20, S. Peters21z & R. A. Stahel
  Annals of Oncol, Volume 31 – Issue 12 – 2020 , pages 1734-1745
  https://doi.org/10.1016/j.annonc.2020.09.009

 

• Outcomes of surgical resection after neoadjuvant chemoimmunotherapy in stage IIIA non-small-cell lung cancer: Findings from the NADIM study
  Alejandra Romero Román* 1, Jose Luis Campo-Cañaveral de la Cruz*,1, Ivan Macía 2, Ignacio Escobar Campuzano 3, Santiago Figueroa Almánzar 4, María Delgado Roel 5, Carlos Gálvez Muñoz .6, Eva Mª García Fontán7, Ignacio Muguruza Trueba 8, Laura Romero Vielva9, Jose Ramon Cano Garcia10, Elisabeth Martinez Tellez 11, Concepción Partida González 12, Marcelo Fernando Jiménez López 13, Unai Jiménez Maestre 14, Roberto Mongil Poce 15, David Sánchez Lorente 16, Antonio Álvarez Kindelan 17, Mariano Provencio Pulla 18
  Eur J Cardiothorac Surg- DOI: 10.1093/ejcts/ezab007- https://pubmed.ncbi.nlm.nih.gov/33661301/

• Safety and efficacy of crizotinib in patients with advanced or metastatic ROS1-rearranged lung cancer (EUCROSS): A European phase 2 clinical trial
  Sebastian Michels, MD, Bartomeu Massutí, MD, Prof. Hans-Ulrich Schildhaus, MD, Jeremy Franklin, PhD, Martin Sebastian, MD, Enriqueta Felip, MD, Prof. Christian Grohé, MD, Delvys Rodriguez-Abreu, MD, Diana S.Y. Abdulla, MD, Helge Bischoff, MD, Prof. Christian Brandts, MD, Enric Carcereny, MD, Jesús Corral, MD, Anne-Marie C. Dingemans, PhD, Eva Pereira, Jana Fassunke, PhD, Rieke N. Fischer, MD, Masyar Gardizi, MD, Lukas Heukamp, MD, Amelia Insa, MD, Anna Kron, Dipl. Ges.-Oek, Roopika Menon, PhD, Thorsten Persigehl, MD, Prof. Martin Reck, MD, Richard Riedel, MD, Sacha I. Rothschild, MD, Andreas H. Scheel, MD, Matthias Scheffler, MD, Petra Schmalz, PhD, Prof. Egbert F. Smit, PhD, Meike Limburg, Mariano Provencio, PhD, Niki Karachaliou, PhD, Prof. Sabine Merkelbach-Bruse, PhD, Prof. Martin Hellmich, PhD, Lucia Nogova, MD, Prof. Reinhard Büttner, MD, Rafael Rosell, PhD, Prof. Jürgen Wolf, MD,∗,
  Journal of thoracic oncology DOI: https://doi.org/10.1016/j.jtho.2019.03.020

• Corinne Faivre-Finn, Michael Snee, Linda Ashcroft, Wiebke Appel, Fabrice Barlesi, Adityanarayan Bhatnagar, Andrea Bezjak, Felipe Cardenal, Pierre Fournel, Susan Harden, Cecile Le Pechoux, Rhona McMenemin, Nazia Mohammed, Mary O’Brien, Jason Pantarotto, Veerle Surmont, Jan P Van Meerbeeck, Penella J Woll, Paul Lorigan, Fiona Blackhall, for the CONVERT Study Team. Concurrent once-daily versus twice-daily chemoradiotherapy in patients with limited-stage small-cell lung cancer (CONVERT): an open-label, phase 3, randomised, superiority trial. www.thelancet.com/oncology Published online June 19, 2017 http://dx.doi.org/10.1016/S1470-2045(17)30318-2

• Rosell R, Dafni U, Felip E, Curioni-Fontecedro A, Gautschi O, Peters S, Massutí B, Palmero R, Aix SP, Carcereny E, Früh M, Pless M, Popat S, Kotsakis A, Cuffe S, Bidoli P, Favaretto A, Froesch P, Reguart N, Puente J, Coate L, Barlesi F, Rauch D, Thomas M, Camps C, Gómez-Codina J, Majem M, Porta R, Shah R, Hanrahan E, Kammler R, Ruepp B, Rabaglio M, Kassapian M, Karachaliou N, Tam R, Shames DS, Molina-Vila MA, Stahel RA; BELIEF collaborative group. Erlotinib and bevacizumab in patients with advanced non-small-cell lung cancer and activating EGFR mutations (BELIEF): an international, multicentre, single arm, phase 2 trial. Lancet Respir Med. 2017 Apr 10. pii: S2213-2600(17)30129-7. doi: 10.1016/S2213 2600(17)30129-7. [Epub ahead of print]

• Peters S, Stahel RA, Dafni U, Ponce Aix S, Massutí B, Gautschi O, Coate L, López Martín A, van Heemst R, Berghmans T, Meldgaard P, Cobo Dols M, Garde Noguera J, Curioni-Fontecedro A, Rauch D, Mark MT, Cuffe S, Biesma B, van Henten AM, Juan Vidal Ó, Palmero Sanchez R, Villa Guzmán JC, Collado Martin R, Peralta S, Insa A, Summers Y, Láng I, Horgan A, Ciardiello F, de Hosson S, Pieterman R, Groen HJ, van den Berg PM, Zielinski CC, Chittazhathu Kurian Kuruvilla Y, Gasca-Ruchti A, Kassapian M, Novello S, Torri V, Tsourti Z, Gregorc V, Smit EF; EMPHASIS-lung Collaborative Group. Randomized Phase III Trial of Erlotinib versus Docetaxel in Patients with Advanced Squamous Cell Non-Small Cell Lung Cancer Failing First-Line Platinum-Based Doublet Chemotherapy Stratified by VeriStrat Good versus VeriStrat Poor. The European Thoracic Oncology Platform (ETOP) EMPHASIS-lung Trial. J Thorac Oncol. 2017 Apr;12(4):752-762. doi: 10.1016/j.jtho.2016.12.017. Epub 2016 Dec 23.

• Romain Corre, Laurent Greillier, Hervé Le Caër, Clarisse Audigier-Valette, Nathalie Baize, Henri Bérard, Lionel Falchero, Isabelle Monnet, Eric Dansin, Alain Vergnenègre, Marie Marcq, Chantal Decroisette, Jean-Bernard Auliac, Suzanna Bota, Régine Lamy, Bartomeu Massuti, Cécile Dujon, Maurice Pérol, Jean-Pierre Daurès, Renaud Descourt, Hervé Léna, Carine Plassot and Christos Chouaïd. Use of a Comprehensive Geriatric Assessment for the Management of Elderly Patients With Advanced Non–Small-Cell Lung Cancer: The Phase III Randomized ESOGIA-GFPC-GECP 08-02 Study. Published online before print February 16, 2016, doi: 10.1200/JCO.2015.63.5839 JCO February 16, 2016 JCO635839

• Vergnenegre, B. Massuti, F.de Marinis, E. Carcereny,  E. Felip, P. Do,J.M.Sanchez, L. Paz-Arez, MD,g,i Christos Chouaid, R. Rosell, on behalf of the Spanish Lung Cancer Group, Italian Association of Thoracic Oncology, and French Lung Cancer Group. Economic Analysis of First-Line Treatment with Erlotinib in an EGFR-Mutated Population with Advanced NSCLC. J Thorac Oncol. 2016 Jun;11(6):801-7. doi: 10.1016/j.jtho.2016.02.004. Epub 2016 Feb 18.

• Niki Karachaliou, Clara Mayo-de las Casas, Cristina Queralt, Itziar de Aguirre, Boris Melloni, Felip Cardenal, Ramon Garcia-Gomez, Bartomeu Massuti, José Miguel Sánchez, Ruth Porta, Santiago Ponce-Aix, Teresa Moran, Enric Carcereny, Enriqueta Felip, Isabel Bover, Amelia Insa, Noemí Reguart, Dolores Isla,  Alain Vergnenegre, Filippo de Marinis, Radj Gervais, Romain Corre, Luis Paz-Ares, Daniela Morales-Espinosa, Santiago Viteri, Ana Drozdowskyj, Núria Jordana-Ariza, Jose Luis Ramirez-Serrano, Miguel Angel Molina-Vila, Rafael Rosell, on behalf of the Spanish Lung Cancer Group. Shorter survival to erlotinib associated with the presence of the EGFR L858R mutation in blood: a prespecified analysis of the EURTAC trial. JAMA Oncol 2015 May;1(2):149-57. doi: 10.1001/jamaoncol.2014.257.

• T. Moran, J. Wei, M. Cobo, X. Qian, M. Domine, Z. Zou, I. Bover, L. Wang, M. Provencio, L. Yu, I. Chaib, C. You, B. Massuti, Y. Song, A. Vergnenegre, H. Lu, G. Lopez-Vivanco, W. Hu, G. Robinet, J. Yan, A. Insa, X. Xu, M. Majem, X. Chen, R. de las Peñas, N. Karachaliou, M. A. Sala, Q. Wu, D. Isla, Y. Zhou, N. Baize, F. Zhang, J. Garde, P. Germonpre, S. Rauh, H. ALHusaini, M. Sanchez-Ronco, A. Drozdowskyj, J. J. Sanchez, C. Camps, B. Liu, R. Rosell, on behalf of the Spanish Lung Cancer Group, the French Lung Cancer Group and the Comprehensive Cancer Centre of Drum Tower Hospital in Nanjing.  Two biomarker-directed randomized trials in European and Chinese patients with non-small-cell lung cancer: The BRCA1-RAP80 Expression Customization (BREC) studies. Annals of Oncology 25: 2147–2155, 2014.. doi:10.1093/annonc/mdu389. Published online 27 August 2014

• Miguel A Molina-Vila Jordi Bertran-Alamillo, Amaya Gascó, Clara Mayo-de-las-Casas, María Sánchez-Ronco, Laia Pujantell-Pastor, Laura Bonanno, Adolfo G. Favaretto, Andrés F Cardona, Alain Vergnenègre, Margarita Majem, Bartomeu Massuti, Teresa Morán, Enric Carcereny, Santiago Viteri and Rafael Rosell. Nondisruptive p53 mutations are associated with shorter survival in advanced non-small-cell lung cancer patients. Clin Cancer Res 2014 Sep 1;20(17):4647-59. doi: 10.1158/1078-0432.CCR-13-2391. Epub 2014 Apr 2.

• Karachaliou N, Gimenez-Capitan A, Drozdowskyj A, Viteri S, Moran T, Carcereny E, Massuti B, Vergnenegre A, de Marinis F, Molina M.A, Teixido C, Rosell R. “ROR1 as a novel therapeutic target for EGFR-mutant non-small-cell lung cancer patients with the EGFR T790M mutation” Translational Lung Cancer Research 2014;3(3):122-130

• Noemi Reguart, Rafael Rosell, Felipe Cardenal, Andres F. Cardona, Dolores Isla, Ramon Palmero, Teresa Moran, Christian Rolfo, M. Cinta Pallarès, Amelia Insa,Enric Carcereny, Margarita Majem, Javier De Castro, Cristina Queralt,Miguel A. Molina, Miquel Taron.  Phase I/II trial of vorinostat (SAHA) and erlotinib for non-small celllung cancer (NSCLC) patients with epidermal growth factor receptor(EGFR) mutations after erlotinib progression. Lung Cancer. 2014 May;84(2):161-7. doi: 10.1016/j.lungcan.2014.02.011. Epub 2014 Mar 2

• Translational Lung Cancer Research. Focussed Issue: The 10th Congress of the Spanish Lung Cancer Group. Transl Lung Cancer Res 2014;3(2):64-119

• Costa C, Molina MA, Drozdowskyj A, Giménez-Capitán A, Bertran-Alamillo J, Karachaliou N, Gervais R, Massuti B, Wei J, Moran T, Majem M, Felip E, Carcereny E, Garcia-Campelo R, Viteri S, Taron M, Ono M, Giannikopoulos P, Bivona T, Rosell R. “The Impact of EGFR T790M Mutations and BIM mRNA Expression on Outcome in Patients with EGFR-Mutant NSCLC Treated with Erlotinib or Chemotherapy in the Randomized Phase III EURTAC Trial”. Clin Cancer Res. 2014 Apr 1;20(7):2001-10. doi: 10.1158/1078-0432.CCR-13-2233. Epub 2014 Feb 3

• Bonano L, Costa C, Majem M, Sánchez JJ, Gímenez-Capitán A, Rodríguez I, Vergnenegre A, Massutí B, Favaretto A, Rugge M, Pallarés C, Tarón M, Rosell R. The predictive value of 53BP1 and BRCA1 mRNA expression in advanced non-small-cell lung cancer patients treated with first-line platinum-based chemotherapy. Oncotarget 10/2013; 4(10):1572-81.

• B. Massuti, JM Sanchez, F. Hernando-Trancho, N. Karachaliou, R.Rosell. Are we ready to use biomarkers for staging, prognosis and treatment selection in early-stage non-small-cell lung cancer?  Transl Lung Cancer Res 2013;2(3):208-221

• P. Garrido, R. Rosell, A. Arellano, F. Andreu, M. Dómine,A. Perez-Casas, F. Cardenal, MM Arnaiz, Teresa Moránb, R. Morera,D. Isla, J. Valencia,M. Cobo, R. Delgado, R. García-Gómez, F. Calvo, J. Zamorai, A. Ramos, B. Massutí. Randomized phase II trial of non-platinum induction or consolidation chemotherapy plus concomitant chemoradiation in stage III NSCLC patients:Mature results of the Spanish Lung Cancer Group 0008 study. Lung Cancer 81 (2013) 84– 90

• Karachaliou N, Costa C, Gimenez-Capitan A, Molina-Vila MA, Bertran-Alamillo J, Mayo C, Massuti B, Majem M, Carcereny E, Moran T, Sanchez JJ, Viteri S, Gasco A, Wannesson L, Souglakos J, Jimeno J, Rosell R. BRCA1, LMO4, and CtIP mRNA Expression in Erlotinib-Treated Non-Small-Cell Lung Cancer Patients with EGFR Mutations. J Thorac Oncol. 2013 Mar;8(3):295-300.

• Provencio M, Camps C, Cobo M, De las Peñas R, Massuti B, Blanco R, Alberola V, Jimenez U, Delgado JR, Cardenal F, Tarón M, Ramírez JL, Sanchez A, Rosell R. Prospective assessment of XRCC3, XPD and Aurora kinase A single-nucleotide polymorphisms in advanced lung cancer. Cancer Chemother Pharmacol. 2012 Dec;70(6):883-90.

• Rosell R, Carcereny E, Gervais R, Vergnenegre A, Massuti B, Felip E, Palmero R, Garcia-Gomez R, Pallares C, Sanchez JM, Porta R, Cobo M, Garrido P, Longo F, Moran T, Insa A, De Marinis F, Corre R, Bover I, Illiano A, Dansin E, de Castro J, Milella M, Reguart N, Altavilla G, Jimenez U, Provencio M, Moreno MA, Terrasa J, Muñoz-Langa J, Valdivia J, Isla D, Domine M, Molinier O, Mazieres J, Baize N, Garcia-Campelo R, Robinet G, Rodriguez-Abreu D, Lopez-Vivanco G, Gebbia V, Ferrera-Delgado L, Bombaron P, Bernabe R, Bearz A, Artal A, Cortesi E, Rolfo C, Sanchez-Ronco M, Drozdowskyj A, Queralt C, de Aguirre I, Ramirez JL, Sanchez JJ, Molina MA, Taron M, Paz-Ares L; on behalf of the Spanish Lung Cancer Group in collaboration with the Groupe Français de Pneumo-Cancérologie and the Associazione Italiana Oncologia Toracica. Erlotinib versus standard chemotherapy as first-line treatment for European patients with advanced EGFR mutation-positive non-small-cell lung cancer (EURTAC): a multicentre, open-label, randomised phase 3 trial. Lancet Oncol. 2012 Mar;13 (3):239-246. Epub 2012 Jan 26.

• Massuti B, Cobo M, Camps C, Dómine M, Provencio M, Alberola V, Viñolas N, Rosell R, Tarón M, Gutiérrez-Calderón V, Lardelli P, Alfaro V, Nieto A, Isla D. Trabectedin in patients with advanced non-small-cell lung cancer (NSCLC) with XPG and/or ERCC1 overexpression and BRCA1 underexpression and pretreated with platinum. Lung Cancer. 2012 Jun;76(3):354-61.

• Santarpia M, Magri I, Sanchez-Ronco M, Costa C, Molina-Vila MA, Gimenez-Capitan A, Bertran-Alamillo J, Mayo C, Benlloch S, Viteri S, Gasco A, Mederos N, Carcereny E, Taron M, Rosell R. mRNA expression levels and genetic status of genes involved in the EGFR and NF-κB pathways in metastatic non-small-cell lung cancer patients. J Transl Med. 2011 Sep 27;9:163. doi: 10.1186/1479-5876-9-163.

• Bover I, Rolfo C, Jantus-Lewintre E, Sirera R, Camps C. Chaib I, Ramirez-Serrano JL. Benlloch s, Molina-Vila MA, Simonetti S, Costa C, Gimenez-Capitan A, Mendez P, Taron M,  Rosell R. Fifth Educational Symposium of the Spanish Lung Cancer Group: Report on the Molecular Biology Workshop. Lung Cancer, 74 (3), 535-543, des.  2011

• Rosell R, Molina MA, Costa C, Simonetti S,  Gimenez-Capitan A, Bertran-Alamillo J, Mayo C, Moran T, Mendez P, Cardenal  F, Isla D, Provencio M, Cobo M, Insa A, Garcia-Campelo R, Reguar N, Majem M, Viteri  S, Carcereny E, Porta R,  Massuti B, Queralt C, de Aguirre I, Sanchez JM, M, Sanchez-Ronco M, Mate JL, Ariza A, Benlloch S, Sanchez JJ, Taron M. Pre-treatment EGFR T790M mutation and BRCA1 mRNA expression in erlotinib-treated advanced non-small-cell lung cancer patients with EGFR mutation. Clin Cancer Res 17 (5), 1-9 march 2011

• Porta R, Sánchez-Torres JM, Paz-Ares L, Massutí B, Reguart N, Mayo C, Lianes P, Queralt C, Guillem V, Salinas P, Catot S, Isla D, Pradas A, Gúrpide A, de Castro J, Polo E, Puig T, Tarón M, Colomer R, Rosell R. Brain metastases from lung cancer responding to erlotinib: the importance of EGFR mutation. Eur Respir J. 2011 Mar;37(3):624-31. doi: 10.1183/09031936.00195609. Epub 2010 Jul 1.

• Salazar F, Molina MA, Sanchez-Ronco M, Moran T, Ramirez JL, Sanchez JM, Stahel R, Garrido P, Cobo M, Isla D, Bertran-Alamillo J, Massuti B, Cardenal F, Manegold C, Lianes P, Trigo JM, Sanchez JJ, Taron M, Rosell R. First-line therapy and methylation status of CHFR in serum influence outcome to chemotherapy versus EGFR tyrosine kinase inhibitors as second-line therapy in stage IV non-small-cell lung cancer patients  Lung Cancer. 2011 Apr;72(1):84-91.

• Viñolas N, Provencio M, Reguart N, Cardenal F,  Alberola V, Sánchez-Torres J.M, Barón FJ, Cobo M, Maestu I,  Moreno I, Mesía C, Izquierdo A, Felip E, López-Brea, Márquez A, Sánchez-Ronco M, Tarón M, Santarpia MC, Rosell R, on behalf of the Spanish Lung Cancer Group. Single nucleotide polymorphisms in MDR1 gen correlates with outcome in advanced non-small-cell lung cancer patients treated with cisplatin plus vinorelbine. Lung Cancer 71 (2011) 191–198

• Jantus-Lewintre E, Sanmartín E, Sirera R, Blasco A, Sanchez JJ, Tarón M, Rosell R, Camps C. Combined VEGF-A and VEGFR-2 concentrations in plasma: diagnostic and prognostic implications in patients with advanced NSCLC.  Lung Cancer. 2011 Nov;74(2):326-31.

2010

• Carcereny E, Ramirez JL, Sanchez-Ronco M, Isla D, Cobo M, Moran T, de Aguirre I, Okamoto T, Wei J, Provencio M, Lopez-Vivanco G, Camps C, Domine M, Alberola V, Sanchez JM, Massuti B, Mendez P, Taron M, Rosell R. Blood-based CHRNA3 single nucleotide polymorphism and outcome in advanced non-small-cell lung cancer patients. Lung Cancer, Volume 68, Issue 3 , Pages 491-497, June 2010  PubMed PMID: 19733931.

• Simonetti S, Molina MA,  Queralt C,  de Aguirre I, Mayo C,  Bertran-Alamillo J,  Sanchez JJ,   Gonzalez-Larriba JL, Jimenez U, Isla D, Moran T, Viteri S, Camps C, Garcia-Campelo R,  Massutí B,  Benlloch S, Ramon y Cajal S,  Taron M, Rosell R. Detection of EGFR mutations with mutation-specific antibodies in stage IV non-small-cell lung cancer. Simonetti et al. Journal of Translational Medicine 2010, 8:135.  http://www.translational-medicine.com/content/8/1/135

• Felip E, Rosell R, Maestre JA, Rodríguez-Paniagua JM, Moran T, Astudillo J, Alonso G, Borro JM, González-Larriba JL, TorresA, Camps C, Guijarro R, Isla D, Aguilo R, Alberola V, Padilla J, Sánchez-Palencia A, Sánchez JJ, Hermosilla E, Massuti B. Preoperative Chemotherapy Plus Surgery Versus Surgery Plus Adjuvant Chemotherapy Versus Surgery Alone in Early-Stage Non–Small-Cell Lung Cancer. Journal of Clinical Oncology, Vol 28, No 19 (July 1), 2010: pp. 3138-3145

• Salazar F, Molina MA, Sanchez Ronco M, Moran T, Ramirez JL; Sanchez J.M, Stahel R., Garrido P, Cobo M, Isla D, Bertran-Alamillo J, Massuti B, Cardenal F, Manegold C, Lianes P, Trigo J.M, Sanchez J.J, Taron M, Rosell R. First-line therapy and methylation status of CHFR in serum influence outcome to chemotherapy versus EGFR tyrosine kinase inhibitors as second-line therapy in stage IV non-small-cell lung cancer patients. Lung Cancer. 2011 Apr;72(1):84-91. doi: 10.1016/j.lungcan.2010.07.008. Epub 2010 Aug 11.)

• Provencio M, de Las Peñas R, Camps C, Artal A, Massuti B, Cobo M, Pérez FJ, Sánchez A, Rosell. Cisplatin plus vinorelbine as first-line treatment for advanced non-small-cell lung cancer: Is a hemogram on day 8 essential? Lung Cancer 2010, 68 (3): 415-419 PubMed PMID: 19695734.

 

2009

• Di Maio M, Lama N, Morabito A, Smit EF, Georgoulias V, Takeda K, Quoix E, Hatzidaki F, Wachters FM, Gebbia V, Tsai C-M, Camps C, Schuette  W, Chiodini P, Piccirillo MC, Perrone F, Gallo C, Gridelli  C. Clinical assessment of patients with advanced non-small-cell lung cancer eligible for second-line chemotherapy: A prognostic score from individual data of nine randomised trials. European Journal of Cancer European Journal of Cancer, 2009  Vol. 46, Issue 4, Pages 735-743

• Rosell R, Moran T, Queralt C, Porta R, Cardenal F, Camps C, Majem M, Lopez-Vivanco G, Isla D, Provencio M, Insa A, Massuti B, Gonzalez-Larriba JL, Paz-Ares L, Bover I, Garcia-Campelo R, Moreno MA, Catot S, Rolfo C, Reguart N, Palmero R, Sánchez JM, Bastus R, Mayo C, Bertran-Alamillo J, Molina MA, Sanchez JJ, Taron M; Spanish Lung Cancer Group Screening for epidermal growth factor receptor mutations in lung cancer. N Engl J Med. 2009 Sep 3;361(10):958-67. Epub 2009 Aug 19

• Rafael Rosell, Laia Perez-Roca, Jose Javier Sanchez, Manuel Cobo, Teresa Moran, Imane Chaib, Mariano Provencio, Manuel Domine, Maria Angeles Sala, Ulpiano Jimenez, Pilar Diz, Isidoro Barneto, Jose Antonio Macias, Ramon de las Peñas, Silvia Catot, Dolores Isla, Jose Miguel Sanchez,  Rafael Ibeas, Guillermo Lopez-Vivanco, Juana Oramas, Pedro Mendez, Noemi Reguart, Remei Blanco, Miquel Taron. Customized Treatment in Non-Small-Cell Lung Cancer Based on EGFR Mutations and BRCA1 mRNA Expression. PLoS One. 2009;4(5):e5133. Epub 2009 May 5.

• Mariano Provencio, Carlos Camps, Vicente Alberola, Bartomeu Massuti, Nuria Viñolas Dolores Isla, Manuel Dómine, Isabel Millán, Manuel Cobo, Rafael Rosell. Lung cancer and treatment in elderly patients: The Achilles Study. Lung Cancer. 2009 Oct;66(1):103-6.

• Garrido P, Rosell R, Massutí B, Cardenal F, Alberola V, Dómine M, Maeztu I, Ramos A, Arellano A; Spanish Lung Cancer Group 0008 Investigators. Predictors of long-term survival in patients with lung cancer included in the randomized Spanish Lung Cancer Group 0008 phase II trial using concomitant chemoradiation with docetaxel and carboplatin plus induction or consolidation chemotherapy. Clin Lung Cancer. 2009 May;10(3):180-6.

• Vega Iranzo, Rafael Sirera, A. Carrato, Andrea Cabrera, Eloísa Jantus, Ricardo Guijarro, Elena Sanmartín, Ana Blasco, Mireia Gil, L. Gómez-Aldavarí, J.L.González-Larriba, B. Massuti, A. Velasco, M. Provencio, Rafael Rosell, Carlos Camps. Phase II clinical trial with gemcitabine and paclitaxel sequential monotherapy as first-line treatment of advanced non-small cell lung cancer (GECP 01-04). Clin Lung Cancer 2009 (submitted)

• Bartolucci R, Wei J, Sánchez JJ, Pérez-Roca L, Chaib I, Puma F, Farabi R, Mendez P, Roila F, Okamoto T, Taron M, Rosell R.  XPG mRNA expression levels modulate prognosis in resected non-small-cell lung cancer in conjunction with BRCA1 and ERCC1 expression. Clin Clin Lung Cancer. 2009 Jan;10(1):47-52.

 

2008

• Sirera R, Gil M, Blasco A, Cabrera A, Safont MJ, Iranzo V, Cayuela D, Rosell R, Camps C. Retrospective analysis of the frequency of p16 protein inactivation in plasma in patients with locally advanced non-small cell lung cancer. Lung Cancer 2008 Jul;61(1):104-8

• Safont MJ, Artal-Cortes A, Sirera R, Gómez-Codina J, González-Larriba JL, Barneto I, Carrato A, Isla D, Rosell R, Camps C. Retrospective study of efficacy and toxicity on patients older than 70 years within a randomized clinical trial of two cisplatin-based combinations in patients with small-cell lung cancer. Lung Cancer. 2009 Jan;63(1):83-7. Epub 2008 Jun 13.

• Skrzypski M, Jassem E, Taron M, Sanchez JJ, Mendez P, Rzyman W, Gulida G, Raz D, Jablons D, Provencio M, Massuti B, Chaib I, Perez-Roca L, Jassem J, Rosell R. Three-gene expression signature predicts survival in early-stage squamous cell carcinoma of the lung. Clin Cancer Res. 2008 Aug 1;14(15):4794-9

• Pignon J-P, Tribodet H, Scagliotti GV, Douillard J-Y, Shepherd FA, Stephens RJ, Dunant A, Torri V, Rosell R, Seymour L, Spiro SG, Rolland E, Fossati R, His P, Ding K, Waller D, Le Chevalier T on behalf of the LACE Collaborative Group. Lung adjuvant cisplatin evaluation (LACE): a pooled analysis of five randomized clinical trials including 4,584 patients. J Clin Oncol 2008 Jul 20;26(21):3552-9

• Rosell R. Lung Cancer Genes. In response to New treatments hope after lung cancer gene found. published in The Times Online, 3 April 2008.

• Rosell R, Manegold C, Moran T, Garrido P, Blanco R, Lianes P, Stahel R, Trigo J, Wei J, Taron M. Can we customize chemotherapy? Individualizing cytotoxic regimens in advanced non-small cell lung cancer. Clin Lung Cancer 2008, Vol 9 (Suppl 2): S76-S82

• Molina MA, Bertran-Alamillo J, Reguart N, Taron M, Castella E, Llatjós M, Costa C, Mayo C, Pradas A, Queralt C, , Botia M, Pérez-Cano M, Carrasco E, Tomas M, Mate J Raz DJ, Ray MR, Kim JY, He B, Taron M, Skrzypski M, Segal M, Gandara DR, Rosell R, Jablons DM.A multigene assay is prognostic of survival in patients with early-stage lung adenocarcinoma. Clin Cancer Res. 2008 Sep 1;14(17):5565-70

• Gridelli C, Ardizzoni A, Ciardello F, Hanna N, Heymach J, Perrone F, Rosell R, Shephard FA, Thatcher N, Vansteenkiste J, De Petris L, Di Maio M, De Marinis F. Second-line treatment of advanced non-small-cell lung cancer. J Thorac Oncol. 2008 Apr;3(4):430-40.

• Douillard J-Y, Rosell R, De Lena M, Riggi M, Hurteloup P, Mahe MA. Impact of post operative radiation therapy (PORT) on survival in completely resected patients with stages I, II or IIIA non-small-cell lung cancer treated with adjuvant chemotherapy in the randomized trial ANITA. Intl J Radiat Oncol Biol Phys 2008 Apr 24. (Epub ahead of print)

• Garrido P, Massutí B, Cardenal F., Alberola V, Dómine M, Maeztu I, Arellano A, Ramos A, Rosell R (on behalf of the Spanish Lung Cancer Group 0008 investigators). Predictors of long-term survival in lung cancer patients included in the randomized Spanish Lung Cancer Group 0008 phase II trial using concomitant chemoradiation with docetaxel and carboplatin plus induction or consolidation chemotherapy. Clinical Lung Cancer, Invited manuscript

• L, Moran T and Rosell R. A sensitive method for detecting EGFR mutations in non-small cell lung cancer samples with few tumor cells. J Thor Oncol 2008 , Vol 3, 11: 1224-1235

• Rosell R , Vergnenegre A, Fournel P,  Massuti B, Camps C , Isla D , Sanchez JM, Moran T, Sirera R and Taron M. Pharmacogenetics in lung cancer for the lay doctor.  Targeted Oncology 2008 , Vol 3 (3): 161-171

• Taron M, Molina MA, Mendez P, Sirera R, Camps C, Felip E, Massuti B, Carrasco E, Benlloch S, Ramon y Cajal S, Mate JL and Rosell R. The practicalities of pharmacogenomic Analysis- The Spanish Lung Cancer Group Experience. Le Nouveau Cancérologue 2008; 1: 1-3

• Rosell R, and Garcia-Campelo, R. Farmacogenómica como instrumento de individualización del tratamiento del cáncer. Formación Médica Continuada en Oncología. Jun 2008 Vol 3, Suppl 1: 71-82

• Perona R, Massuti B, Rosell R. Reflections on the IASLC 12th World Conference on Lung Cancer. Clin Transl Oncol 2008 Feb;10(2):67-9

• Felip E, Rosell R. Permetrexed as second-line therapy for advanced non-small-cell lung cancer (NSCLC).The Clin Risk Manag. 2008 Jun;4(3):579-85.

 

2007

• P. Garrido, JL González-Larriba, A. Insa, M. Provencio, A.Torres, D. Isla, JM. Sánchez, F. Cardenal, M. Domine, J.R Barcelo, V. Tarrazona, A. Varela, R. Aguilo, J. Astudillo, I.Muguruza, A. Artal, F. Hernando-Trancho, B. Massuti, M. Sanchez-Ronco, R. Rosell. Long-Term survival Associated With Complete Resection After Induction Chemotherapy in Stage IIIA (N2) and IIIB (T4N0-1) Non-Small-Cell Lung Cancer Patients: The Spanish Lung Cancer Group Trial 9901. Journal of Clinical Oncology. Vol. 25. No 30. : 4736-4742. October 20 2007

• R.Rosell, M. Taron, JJ. Sánchez, L.Paz Ares. Setting the benchmark for tailoring treatment with EGFR tyrosine kinase inhibitors. Future Medicine. Future Oncol. (2007) 3(3): 277-283

• M. Cobo, D. Isla, B. Massuti, A. Montes, JM. Sanchez, M.Provencio, N.Viñolas, L. Paz-Ares, Guillermo Lopez-Vivanco, M.A. Muñoz, E. Felip, V. Alberola, C. Camps, M. Domine, J.J. Sanchez, M. Sanchez-Ronco, K. Danenberg, M.Taron, D. Gandara, R. Rosell. Customizing Cisplatin Base on Quatitative Excision Repair Cross-Complementing 1 mRNA Expression: A Phase III Trial in Non-Small-Cell Lung Cancer.  Journal of Clinical Oncology.  Vol. 25. No 19: 2747-2754, July 1 2007

 

2006

• R. Rosell, M. Taron, N. Reguzrt, D. Isla, T. Moran. Epidermical Growth Factor Receptor ctivation: How Exon 19 and 21 Mutations Changed our Understanding of the Pathway. Clin Cancer Res 2006; 12 (24): 7222-7231 (Des. 15, 2006)

• R. Rosell, M. Taron, M. Galvez, M.C. Pastor, C. Queralt, A. Pradas, M. Botia, M. Pérez, N. Reguart, T. Moran, J.M. Sánchez, M.L. Amador, J.L. Asensio, B. Massutí, L. Paz Ares en nombre del Grupo Español de Cáncer de Pulmón. Determinación de las mutaciones del receptor del factor de crecimiento epidérmico (EGFR) en pacientes con cáncer de pulmón no microcítico tratados únicamente con erlotinib.  Formación Médica continuada Oncología. 2006

• J-Y. Douillard, R. Rosell, M: de Lena, F. Carpagnano, R. Ramlau, J.L. González-Larriba, T. Grodzki, J. Rodrigues Pereira, A. Le Groumellec, V. Lorusso, C. Clary, A. J. Torres, J. Dahabreh, P.J, Souquet, J. Astudillo, P. Fournel, A. Artal, J. Jassem, L. Koubkova, P. His, M. Riggi, P. Hurteloup. Adjuvant Vinorelbine plus cisplatin versus observation in patients with completely resected stage IB-IIIA NSCLC (Adjuvant Navelbine International Trialist Association [ANITA]): a randomised controlled trial.  The Lancet, Vol. 7: 719-727, sept 2006.

• R. Rosell, M. Cobo, D. Isla, C. Camps, B. Massutí. Pharmacogenomics and gemcitabine. Annals of Oncology, 17, supplement 5): 13-16. may 2006

• R. Rosell, M. Taron, N. Reguart, F. López-Ríos, L. Paz-Ares, J.L. Ramírez, B. Massutí, M. Cuello, D. Jablons. Pharmacogenomics comes of age in selecting patients for Lung Cancer Treatment. 2006 ASCO Educational Book

• R. Rosell, M. Cuello, F. Ceccere, MC Santarpia, N. Reguart, E. Felip, M. Taron. Treatment of non-small-cell lung cancer and pharmacogenomics: where ve are and where we are going. Curr Opin Oncol. 2006, 18 (2): 135-143.

• C. Camps B. Massuti, A. Jiménez, I. Maestu, R. García Gómez, D. Isla, J.L. González, D. Almenar, A. Blasco, R. Rosell, A.Carrato, N. Viñolas, N. Batista, C. García Girón, A. Galán, M. López, R. Blanco, M. Provencio, P. Diz, E.Felip. On behalf of the Spanish Lung Cancer Group. Randomized Phase III Study of Three-Weekly versus Weekly Docetaxel in Pretreated Advanced Non-Small Cell Lung Cancer: A Spanish Lung Cancer Group Trial. Ann Oncol 2006 17(3): 467-472

• R. de las Peñas, M. Sanchez-Ronco, V. Alberola,  M. Taron, C. Camps, R. Garcia-Carbonero, B. Massuti, C. Queralt, M. Botia, R. Garcia-Gomez, D. Isla, M. Cobo, A. Artal, M.A. Muñoz, I. Bover, D. Almenar, M.Jimenez, J. Terrasa, P. Diz, J.L. Gonzalez-Larriba, R. Barcelo, B. Medina, F. Cardenal, M. Santarpia, F.Cecere, P. Mendez, J.J. Sanchez, R. Rosell, on behalf of the Spanish Lung Cancer Group. Polymorphisms in DNA repair genes modulate survival in cisplatin-plus-Gemcitabine-Treated NSCLC.  Ann Oncol 2006, 17 (4): 669-675

 

2005

• H. Cortes-Funes, C. Gomez,  R. Rosell, P. Valero, C. Garcia-Giron, A. Velasco, A. Izquierdo, P. Diz, C.Camps, D. Castellanos, V. Alberola, F. Cardenal, J.L. Gonzalez-Larriba, JM Vieitez, I. Maeztu, JJ. Sanchez, C. Queralt, C. Mayo, P. Mendez, T. Moran , M. Taron, on behalf of the Spanish Lung Cancer Group. Epidermal Growth Factor Receptor Activating Mutations in Spanish Gefitinib-Treated Non-Small-Cell Lung Cancer Patients. Annals of Oncology, 16: 1081-1086, 2005

• Taron M, Ichinose Y, Rosell R, Mok T, Massuti B, Zamora L, Mate JL, Maneglod C, Ono M, Queralt C, Jahan T, Sánchez JJ, Sánchez-Ronco  M, Hsue V, Jablons D, Sánchez JM, Moran T. Activating Mutations in the in the Tyrosine Kinase Domain of the Epidermal Growth Factor Reseptor are associated with Improved Survival in Gefitinib-Treated Chemorefractory Lung Adenorcarcinomas. Clinical Cancer Research 2005; 11:5878-5885

• Rosell R, Ichinose Y, Taron M, Sarries C, Queralt C, Mendez P, Sanchez JM, Nishiyama I, Moran T, Cirauqui B, Mate JL, Besse B, Reguart N, Perez M, Sanchez JJ. Mutations in the tyrosine kinase domain of the EGFR gene associated with gefitinib response in non-small-cell lung cancer.  Lung Cancer , 2005, 50, 25-33

• C. Camps, E. Felip, JM. Sánchez, B. Massutí, A. Artal, L. Paz-Ares, A. Carrato, V. Alberola, A. Blasco, J: Baselga, L. Astier, M. Voi, R. Rosell. Phase II trial of the novel taxane BMS-184476 as second-line in NSCLC. Annals of Oncology, 2005 16(4) 597-601

• R. Rosell, E. Felip, N. Reguart, T. Moran. Crossing the rubicon in lung adenocarcinoma: the conundrum of EGFR tyrosine kinase mutations. Future Oncol.(2005) 1(3), 319-322

• J.L. Ramirez ,R. Rosell, M. Taron, M. Sanchez-Ronco, V. Alberola, R.de las Peñas, J.M. Sanchez, T.Moran, C. Camps, B. Massuti, J.J. Sanchez, F. Salazar, S. Catot, on behalf of the Spanish Lung Cancer Group. 14–3–3s methylation in pre-treatment serum circulating DNA of cisplatin plus gemcitabine-treated non-small-cell lung cancer patients predicts survival. JCO. Vol. 23, nº 30: 9105-9112, desember, 2005

• R. Rosell, M. Cobo, D. Isla, J.M. Sánchez, M. Taron, G. Altavilla, M Santarpia, T. Moran, O. Etxaniz. Applications of genomics in NSCLC. Lung Cancer, 49 Suppl. (2005) 33-40.

 

2004

• Rosell R, Taron M, Ariza A, Barnadas A, Mate JL, Reguart M, Margeli M, Felip E, Mendez P, Garcia-Campelo R. Molecular predictors of response to chemotherapy in lung cancer. Semin Oncol 2004;31:20-27 (Suppl 1)

• Rosell R. Towards customized trastuzumab in HER-2/neu-overexpresseing non-small-cell lung cancers. J Clin Oncol 2004;22:1-3 (Editorial)

• Rosell R, Danenberg KD, Alberola V, Bepler G, Sanchez JJ, Camps C, Provencio M, Isla D, Taron M, Diz P, Artal A. Ribonucleotide reductase messenger RNA expression and survival in gemcitabine/cisplatin-treated advanced non-small cell lung cancer patients. Clin Cancer Res 2004;10:1318-1325

• Rosell R, Sanchez JM, Taron M, Moran T, Canela M, Ciuraqui B, Felip E, Massuti B, Camps C. Pemetrexed in previously treated non-small-cell lung cancer. Oncology 2004;18(suppl 5):63-71
• Rosell R, Felip E, Taron M, Majo J, Mendez P, Sanchez-Ronco M, Queralt C, Sanchez JJ, Maestre J.  Gene expression as a predictive marker of outcome in stage IIB-IIIA-IIIB non-small cell lung cancer after induction gemcitabine-based chemotherapy followed by resectional surgery. Clin Cancer Res 2004;10 (suppl):4215s-4219s
• Alberola V, Sarries C, Rosell R, Taron M, de las Peñas R, Camps C, Massuti B, Insa A, Garcia-Gomez R, Isla D, Artal A, Muñoz MA, Cobo M, Bover I, Gonzalez-Larriba JL, Terrasa J, Almenar D, Barcelo R, Diz P, Sanchez-Ronco M, Sanchez JJ. Effect of the methylenetetrahydrofolate C677T polymorphism on patients with cisplatin/gemcitabine-treated stage IV non-small-cell lung cancer patients. Clin Lung Cancer 2004;5:360-365
• Isla D, Sarries C, Rosell R, Alonso G, Domine M, Taron M, Lopez-Vivanco G, Camps C, Botia M, Nuñez L, Sanchez-Ronco M, Sanchez JJ, Lopez-Brea M, Barneto I, Paredes A,Medina B, Aartal A, Lianes P. Single nucleotide polymorphisms and outcome in docetaxel-cisplatin-treated advanced non-small-cell lung cancer.  Annals of Oncology 2004;15:1194-1203

• Taron M, Rosell R, Felip E, Mendez P, Souglakos J, Sanchez Ronco M, Queralt C, Majo J, Sanchez JM, Sanchez JJ, Maestre J. BRCA1 mRNA expression levels as an indicator of chemoresistance in lung cancer. Hum Mol Gen 2004;13:2443-2449
• Artal-Cortes A, Gomez-Codina J, Gonzalez-Larriba JL, Barneto I, Carrato A, Isla D, Camps C, Garcia-Giron C, Font A, Maestu I, Cambell J, Rosell R on behalf fo he Spanish Lung Cancer Group. Prospective randomized phase III trial of etoposide/cisplatin versus high-dose epirubicin/cisplatin in small-cell lung cancer. Clin Lung Cancer 2004;6:175-183

• Rosell R, Felip E, Garcia-Campelo R, Balaña C. The biology of non-small-cell lung cancer: Identifying new targets for rational therapy. Lung Cancer, vol. 46, issue 2, pp 135-148, Nov. 2004
• Rosell R, Taron M, Sanchez JM, Moran T, Scagliotti G, Isla D, Massuti B, Alberola V, Sanchez JJ. The promise of pharmacogenomics: GEMZAR and ALIMTA. Oncology 2004 Nov; 18 (Suppl 8): 70-6

• Rosell R, Alberola V, Taron M, Sanchez JM on behalf of the Spanish Lung Cancer Group. New approaches to lung cancer treatment. Current Oncology Reports, Dec 6, Suppl 1: S 16-17

 

2003

• Camps C, Sàrries C, Roig B, Sánchez JJ, Queralt C, Sancho, E, Martínez N, Taron M, Rosell R. Assessment of Nucleotide Excision Repair XPD Polymorphisms in the Peripheral Blood of Gemcitabine/Cisplatin-Treated Locally Advanced NSCLC patients. Clinical Lung Cancer, vol 4 nº 4, 237-241, 2003

• Alberola V, Camps C,  Provencio M, Isla D, Rosell R, Vadell C, Bover I, Ruiz-Casado A, Azagra P, Jiménez U, González-Larriba JL, Diz P, Cardenal F, Artal A, Carrato A, Morales S, Sánchez JJ, de las Peñas R, Felip E, López-Vivanco G. Cisplatin/Gemcitabine versus a Cisplatine-Bases Triplet versys Non-Platinum Sequential Doublets in Advanced Non-Small-Cell Lung Cancer: A spanish Lung Cancer Group Phase III Randomized Trial. Journal of clinical Oncology, Vol 21 Nº 17 (september 1), 2003: pp 3207-3213

• Rosell R, Taron M, Alberola V, Massutí B, Felip E, Spanish Lung Cancer Group. Genetic testing for chemotherapy in non-small-cell lung cancer. Lung Cancer vol. 41 ; 97-102 (2003)

• Ramirez JL, Sàrries C, López de Castro P, Roig B, Queralt C, Escuin D, de Aguirre I, Sánchez JM, Manzano JL, Margelí M, Sánchez JJ, Astudillo J, Taron M, Rosell R. Methylation Patterns and K-ras Mutations in Tumor and Paired Serum of Resected NSCLC patients. Cancer Letters, vol. 193, Issue 2. 207-216 (April 2003)

• Rosell R, Taron M, Barnadas A, Scagliotti G, Sarries C, Roig B. Nucleotide Excision Repair Pathways involved in Cisplatin Resistance in NSCLC. Cancer Control, Jul/August 2003, Vol 10 Nº 4: 297-305

• Felip E, Rosell R, Dómine M, Santomé L, Garrido P, Font A, Carrato A, Terrasa J, Vadell C, Mañé JM, Baselga J, on the behalf of the SLCG. Sequential dose-dense paclitaxel followed by topotecan in untreated extensive-stage SCLC: a SLCG  phase II study. Annals of Oncology Vol 14 Nº 10: 1549-1554, october 2003

• Rosell R, Crino L, Danenberg K, Scagliotti G, Bepler G, Taron M, Alberola M, Provencio M; Camps C, De Marinis F, Sánchez JJ, de las Peñas R. Targeted Therapy in combination with Gemcitabine in Non-Small Cell Lung Cancer. Seminars in Oncology, Vol 30 nº 4 Suppl 10 (August), 2003 pp 19-25

• Cardenal F, Dómine M, Massutí B, CArrato A, Felip E, Garrido P, Juan O, Artal A, Barneto I, López-Vivanco G, Balcells M, Rosell R. Three-week schedule of ironotecan and cisplatin in advanced non-small cell lung cancer: a multicentre phase II study. Lung Cancer, vol. 39/2, 201-207, 2003

 

2002

Rosell R, Taron M, Sàrries C, Queralt C, Roig B. B-tubulin mutational analysis: tantalizing findings. Lung Cancer, Letter to the Editor Vol 38 Issue 1 (october, 2002); 99-100

• Rosell R, Lord Reginald VN, Taron M, Reguart N. DNA repair and cisplatin resistance in NSCLC. Lung Cancer, vol 38 issue 3: 217-227 (Des. 02)

• Rosell R, on the behalf of the Spanish Lung Cancer Group, Fossella F, Milas F. Molecular markets and targeted therapy with novel agents: prospects in the treatment of NSCLC. Lung Cancer, vol 38,  supl. 4, 43-49 (Des. 02)

• Sàrries C, Haura EB, Roig B, Taron M, Abad A, Scagliotti G, Rosell R. Pharmacogenomic strategies for developing customized chemotherapy in NSCLC. Pharmacogenomics (2002) 3 (6), 763-780

• Sánchez, JM, Balañá C, Font A, Sánchez JJ, Manzano JL, Guillot M, Margelí M, Richardet M, Rosell R. Phase II non-randomized study of three diferent sequences of docetaxel and vinorelbine in patients with advanced NSCLC. Lung Cancer , vol 38, issue 3, 309-315 (Des.02)

• Reginald V. N. Lord, Jan Brabender, David Gandara, Vicente Alberola, Carlos Camps, Manuel Domine, Felip Cardenal, José M. Sánchez, Paul H. Gumerlock, Miquel Tarón, José J. Sánchez, Kathleen D. Danenberg, Peter V. Danenberg and Rafael Rosell. Low ERCC1 Expression Correlates with Prolonged Survival after Cisplatin plus Gemcitabine Chemotherapy in Non-Small Cell Lung Cancer. Clinical Cancer Research Vol. 8, 2286-2291, July 2002.

• Monzo M, Taron M, Rosell M. Genetic Analysis of the B-tubulin Gene, TUBB in NSCLC. Journal of the National Cancer Institute, Vol. 94 nº 10, 774-777, May 15, 2002

• Rosell R, Garzemeier U, Betticher DC, Kepppler U, Macha HN, Pirker R, Berthet P, Breau JL, Lianes P, Nicholson M, Ardizzoni A, Chemaissani A, Bogaerts J, Gallant G. Phase III randomised trial comparing paclitaxel/carboplatin with paclitasel/cisplatin in patients with advanced NSCLC: a cooperative multinational trial. Annals of Oncology 13:1539-1549, 2002